Cell Based Assays & Molecular Pharmacology
Ichor Life Sciences offers a broad range of standard and specialized cell based assays and molecular assays to fit any of your in-vitro experiment needs.
Use our specialized screening cascades and cell based assays to quickly translate your product from in-vitro to in-vivo.
Cytotoxicity Assays
Optimized protocols for assessing cytotoxicity of molecules in-vitro. Capable of probing for a variety of cell death & viability markers, in hundreds of in-house cell lines.
High Throughput Cell Screening
Two state-of-the-art quantitative high-content imaging cytometers (IncuCyte S3 ® and Operetta CLS ® confocal system). Capable of performing standard, specialized, and custom cell assays.
3-Dimensional Cell Culture
Proprietary methods for optimized generation & therapeutic screening on spheroids in a variety of cell types.
Stable Cell Line Generation
Generation of stable cell lines through chemotherapy resistance, viral transduction, and other methods.
Cell Migration Assays
Real-time automated imaging of kinetic cell migration, invasion assays, and other cell motility read-outs.
Technical Capabilities
Have Confidence in your Data
When confirming molecular mechanisms, it’s important to verify the findings through multiple techniques. The above data set represents a standard package we provide customers. In this example we are assessing the nuclear localization of an oncology target, as a function of drug concentration.
Through western blot densitometry, quantitative imaging cytometry, and confocal microscopy, we show three identical trends between the three different techniques. Our goal is to help you achieve compelling data sets that move the needle forward on your research.
Spheroid Examples
Glioblastoma Spheroid Screening
Examine your molecule in one of our established in-vitro 3D tumor models. Our high-throughput imaging cytometers can screen hundreds of conditions simultaneously in comparison to current standards of care.
We can generate spheroids of precise dimensions, and have our surgical team implant them into our catalog of in-vivo models.
Optimized Cellular Targeting of Biologics
Our high throughput cell penetrating peptide (CPP) screens are designed to optimize cellular selectivity and organelle tropism based on target cell membrane physicochemistry and intracellular trafficking machinery.
Frequently Asked Questions
Questions we often get from customers
