CT-26 Mouse Model
Colorectal cancer is the third leading cause of cancer-related death. CT-26 is a mouse colon carcinoma that was induced by N-nitroso-N-methylurethane in BALB/c mice. CT-26 is a well established model for the study of physiopathology of colon cancers in humans.
We have profiled the tumorigenicity of CT-26 mouse colon carcinoma as a flank model in BALB/c mice. Our model displays aggressive metastatic tumor kinetics as a syngeneic model for tailored immunotherapeutic drug discovery.
Metastatic potential
CT-26 cells have been shown to metastasize to the liver, lungs, and lymph nodes, making it a valuable model for studying cancer metastasis.
Fast-growing tumors
The CT-26 tumors grow rapidly and can be established easily in mice, which allows for quick testing of potential therapeutic agents.
Immunogenicity
CT-26 tumors are highly immunogenic and induce a strong host immune response, which allows for the study of immunotherapeutic agents.
CT-26 Murine Colorectal Carcinoma Model
CT26 is a well-studied rapid growing highly metastatic carcinoma for both flank and orthotopic models.