PDAC Mouse Model: UNKC6141
Pancreatic cancer is one of the most lethal forms of cancer with pancreatic ductal adenocarcinoma (PDAC) as the most common form. UNKC6141 is a mouse pancreatic ductal adenocarcinoma cell line positive for KRAS and ductal marker CK19 making it a valuable model for examining diagnostic markers and therapeutic drug discovery.
We have characterized UNKC6141 mouse pancreatic ductal adenocarcinoma for analyzing the efficacy of therapies for pancreatic cancer. The genetic profile of UNKC6141 cells mimics the natural progression of PDAC in human mutagenesis.
Metastatic potential
This cell line has metastatic potential in the liver, spleen, small intestines, and lymph nodes.
Aggressive Growth
This cell line displays aggressive growth in both orthotopic and syngeneic (flank) models.
UNKC6141 PDAC Mouse Model
UNKC6141 Pancreatic Ductal Carcinoma Model with high mutational burden.